Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
menGUbiquinone/menaquinone biosynthesis; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). (214 aa)    
Predicted Functional Partners:
menA
1,4-dihydroxy-2-naphthoate; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.
 
  
 0.927
CF8_0462
Trans-hexaprenyltranstransferase; Belongs to the FPP/GGPP synthase family.
 
  0.870
CF8_0445
Isochorismate synthase.
     
 0.709
CF8_0369
FAD dependent oxidoreductase; Belongs to the GcvT family.
     
 0.696
CF8_0367
Flavodoxin/nitric oxide synthase.
     
  0.687
CF8_0599
Glucose-methanol-choline oxidoreductase.
     
  0.647
CF8_1017
NmrA family protein.
     
  0.643
CF8_4215
NmrA family protein.
     
  0.643
menD
2-succinyl-6-hydroxy-2; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.
     
 0.632
CF8_2699
Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
  
 0.628
Your Current Organism:
Nocardioides sp. CF8
NCBI taxonomy Id: 110319
Other names: N. sp. CF8
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