Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CF8_0653Hydrolase. (476 aa)    
Predicted Functional Partners:
CF8_0094
Circadian phase modifier CpmA.
 
  
 0.960
larC
Hypothetical protein; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family.
  
 0.918
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 
  0.876
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.839
CF8_3038
Hypothetical protein.
 
  
 0.835
CF8_3263
PTS system glucose-like transporter subunit IIB.
  
 
  0.821
CF8_1521
Ribulose-bisphosphate carboxylase (large_1); Belongs to the RuBisCO large chain family.
    
  0.819
CF8_1522
Ribulose-1,5-bisphosphate carboxylase/oxygenase.
    
 0.812
CF8_1932
Inosine 5-monophosphate dehydrogenase.
    
  0.778
CF8_2796
Phosphoenolpyruvate-dependent sugar.
     
  0.776
Your Current Organism:
Nocardioides sp. CF8
NCBI taxonomy Id: 110319
Other names: N. sp. CF8
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