Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ahcYS-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (481 aa)    
Predicted Functional Partners:
CF8_1956
B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.970
CF8_3153
Cystathionine beta-synthase.
 
 0.900
CF8_2289
S-adenosylmethionine synthetase.
 
 
 0.845
CF8_0586
Cystathionine gamma-lyase.
  
 0.841
CF8_2890
Cys/Met metabolism pyridoxal-phosphate-dependent.
  
 0.841
CF8_1415
Homoserine dehydrogenase.
  
 
  0.828
CF8_1129
Methionine synthase, vitamin-B12 independent.
  
 
 0.814
CF8_0582
Threonine dehydratase.
   
 
  0.806
CF8_2091
ABC transporter-like protein.
    
   0.801
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
   
 
  0.789
Your Current Organism:
Nocardioides sp. CF8
NCBI taxonomy Id: 110319
Other names: N. sp. CF8
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