Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CF8_1277Putative urate oxidase. (142 aa)    
Predicted Functional Partners:
CF8_1279
Transthyretin; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
 
 
 0.990
CF8_1276
Urate oxidase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
 
  
 0.969
CF8_2640
Dihydroorotase.
 
  
 0.940
CF8_1282
Molybdenum cofactor sulfurylase.
 
     0.887
CF8_1280
Molybdopterin dehydrogenase, FAD-binding.
 
     0.885
CF8_1281
Xanthine oxidase.
 
     0.881
CF8_2641
Hypothetical protein; Belongs to the HpcH/HpaI aldolase family.
 
     0.817
CF8_1283
Amidohydrolase.
 
     0.725
pyrC
Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
    
 0.470
CF8_0366
4Fe-4S ferredoxin iron-sulfur binding protein.
     
  0.464
Your Current Organism:
Nocardioides sp. CF8
NCBI taxonomy Id: 110319
Other names: N. sp. CF8
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.