Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CF8_1507HAD family hydrolase. (290 aa)    
Predicted Functional Partners:
CF8_2451
Endonuclease/exonuclease/phosphatase.
  
 
 0.834
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
  0.804
CF8_2450
5'-nucleotidase domain-containing protein; Belongs to the 5'-nucleotidase family.
 
 
 0.750
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.704
CF8_3487
Aldo/keto reductase.
  
  
 0.693
CF8_4145
EmrB/QacA family drug resistance transporter; Belongs to the major facilitator superfamily.
     
  0.690
CF8_1932
Inosine 5-monophosphate dehydrogenase.
     
  0.688
cmk
Cytidylate kinase.
  
 
  0.684
purH
Hypothetical protein; Bifunctional.
    
  0.669
CF8_1855
CMP/dCMP deaminase.
     
  0.661
Your Current Organism:
Nocardioides sp. CF8
NCBI taxonomy Id: 110319
Other names: N. sp. CF8
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