prcA protein (Nocardioides sp. CF8) - STRING interaction network

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prcA

20S proteasome, A and B subunits; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family. (337 aa)

Predicted Functional Partners:

prcB

0.999

arc

0.991

pafA

0.983

CF8_0106

0.972

CF8_2715

0.871

CF8_1013

0.867

CF8_1970

0.808

CF8_1523

0.785

CF8_1974

0.773

CF8_1977

0.702

Your Current Organism:

Nocardioides sp. CF8

NCBI taxonomy Id: 110319
Other names: N. sp. CF8

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CF8_0106	CF8_1970	CF8_0106	CF8_1970	Hypothetical protein.	Hypothetical protein.	0.585
CF8_0106	arc	CF8_0106	CF8_1967	Hypothetical protein.	Vesicle-fusing ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.	0.923
CF8_0106	pafA	CF8_0106	CF8_1975	Hypothetical protein.	Hypothetical protein; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine.	0.687
CF8_0106	prcA	CF8_0106	CF8_1973	Hypothetical protein.	20S proteasome, A and B subunits; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family.	0.972
CF8_0106	prcB	CF8_0106	CF8_1972	Hypothetical protein.	Proteasome subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family.	0.936
CF8_1013	CF8_1523	CF8_1013	CF8_1523	Mov34/MPN/PAD-1 family protein.	CbbX protein.	0.935
CF8_1013	CF8_2715	CF8_1013	CF8_2715	Mov34/MPN/PAD-1 family protein.	Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.	0.952
CF8_1013	arc	CF8_1013	CF8_1967	Mov34/MPN/PAD-1 family protein.	Vesicle-fusing ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.	0.963
CF8_1013	prcA	CF8_1013	CF8_1973	Mov34/MPN/PAD-1 family protein.	20S proteasome, A and B subunits; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family.	0.867
CF8_1013	prcB	CF8_1013	CF8_1972	Mov34/MPN/PAD-1 family protein.	Proteasome subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family.	0.867
CF8_1523	CF8_1013	CF8_1523	CF8_1013	CbbX protein.	Mov34/MPN/PAD-1 family protein.	0.935
CF8_1523	CF8_1974	CF8_1523	CF8_1974	CbbX protein.	Endonuclease/exonuclease/phosphatase.	0.649
CF8_1523	CF8_2715	CF8_1523	CF8_2715	CbbX protein.	Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.	0.927
CF8_1523	arc	CF8_1523	CF8_1967	CbbX protein.	Vesicle-fusing ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.	0.915
CF8_1523	prcA	CF8_1523	CF8_1973	CbbX protein.	20S proteasome, A and B subunits; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family.	0.785
CF8_1523	prcB	CF8_1523	CF8_1972	CbbX protein.	Proteasome subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family.	0.785
CF8_1970	CF8_0106	CF8_1970	CF8_0106	Hypothetical protein.	Hypothetical protein.	0.585
CF8_1970	arc	CF8_1970	CF8_1967	Hypothetical protein.	Vesicle-fusing ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.	0.879
CF8_1970	prcA	CF8_1970	CF8_1973	Hypothetical protein.	20S proteasome, A and B subunits; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family.	0.808
CF8_1970	prcB	CF8_1970	CF8_1972	Hypothetical protein.	Proteasome subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family.	0.803

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