Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CF8_2180Hypothetical protein. (470 aa)    
Predicted Functional Partners:
CF8_1956
B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
  0.628
CF8_3028
HNH nuclease.
  
     0.609
CF8_1473
HNH nuclease.
  
     0.572
CF8_3874
Hypothetical protein.
  
     0.560
CF8_2181
Aminoglycoside phosphotransferase.
       0.558
CF8_1183
HNH endonuclease.
  
     0.552
CF8_3266
HNH endonuclease.
  
     0.549
CF8_2475
Hypothetical protein.
  
     0.511
CF8_2182
Thioredoxin.
       0.510
CF8_0317
GCN5-related N-acetyltransferase.
  
     0.462
Your Current Organism:
Nocardioides sp. CF8
NCBI taxonomy Id: 110319
Other names: N. sp. CF8
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