CF8_2289 protein (Nocardioides sp. CF8) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

CF8_2289

S-adenosylmethionine synthetase. (131 aa)

Predicted Functional Partners:

ribH

0.975

CF8_1956

0.940

CF8_3347

0.873

CF8_1129

0.862

CF8_3660

0.862

CF8_2270

0.846

ahcY

0.845

CF8_3616

0.845

CF8_3843

0.842

CF8_0039

0.798

Your Current Organism:

Nocardioides sp. CF8

NCBI taxonomy Id: 110319
Other names: N. sp. CF8

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CF8_0039	CF8_2289	CF8_0039	CF8_2289	NAD-dependent epimerase/dehydratase family.	S-adenosylmethionine synthetase.	0.798
CF8_1129	CF8_1956	CF8_1129	CF8_1956	Methionine synthase, vitamin-B12 independent.	B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.969
CF8_1129	CF8_2289	CF8_1129	CF8_2289	Methionine synthase, vitamin-B12 independent.	S-adenosylmethionine synthetase.	0.862
CF8_1129	CF8_3660	CF8_1129	CF8_3660	Methionine synthase, vitamin-B12 independent.	Cystathionine gamma-synthase.	0.591
CF8_1129	ahcY	CF8_1129	CF8_1190	Methionine synthase, vitamin-B12 independent.	S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.	0.814
CF8_1956	CF8_1129	CF8_1956	CF8_1129	B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	Methionine synthase, vitamin-B12 independent.	0.969
CF8_1956	CF8_2289	CF8_1956	CF8_2289	B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	S-adenosylmethionine synthetase.	0.940
CF8_1956	CF8_3660	CF8_1956	CF8_3660	B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	Cystathionine gamma-synthase.	0.942
CF8_1956	ahcY	CF8_1956	CF8_1190	B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.	0.970
CF8_2270	CF8_2289	CF8_2270	CF8_2289	Hypothetical protein.	S-adenosylmethionine synthetase.	0.846
CF8_2270	ribH	CF8_2270	CF8_2274	Hypothetical protein.	6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.	0.750
CF8_2289	CF8_0039	CF8_2289	CF8_0039	S-adenosylmethionine synthetase.	NAD-dependent epimerase/dehydratase family.	0.798
CF8_2289	CF8_1129	CF8_2289	CF8_1129	S-adenosylmethionine synthetase.	Methionine synthase, vitamin-B12 independent.	0.862
CF8_2289	CF8_1956	CF8_2289	CF8_1956	S-adenosylmethionine synthetase.	B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.940
CF8_2289	CF8_2270	CF8_2289	CF8_2270	S-adenosylmethionine synthetase.	Hypothetical protein.	0.846
CF8_2289	CF8_3347	CF8_2289	CF8_3347	S-adenosylmethionine synthetase.	NAD dependent epimerase/dehydratase.	0.873
CF8_2289	CF8_3616	CF8_2289	CF8_3616	S-adenosylmethionine synthetase.	Anthranilate synthase component.	0.845
CF8_2289	CF8_3660	CF8_2289	CF8_3660	S-adenosylmethionine synthetase.	Cystathionine gamma-synthase.	0.862
CF8_2289	CF8_3843	CF8_2289	CF8_3843	S-adenosylmethionine synthetase.	Large-conductance mechanosensitive channel.	0.842
CF8_2289	ahcY	CF8_2289	CF8_1190	S-adenosylmethionine synthetase.	S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.	0.845