Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CF8_2329Ribonuclease. (347 aa)    
Predicted Functional Partners:
CF8_2328
Hypothetical protein.
       0.773
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.756
CF8_3476
Hypothetical protein.
  
     0.715
CF8_1816
Hypothetical protein; Overlaps another CDS with the same product name.
  
     0.709
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
  0.648
CF8_2451
Endonuclease/exonuclease/phosphatase.
   
  0.625
CF8_2450
5'-nucleotidase domain-containing protein; Belongs to the 5'-nucleotidase family.
   
  0.613
CF8_3475
PE-PGRS family protein.
  
     0.606
CF8_1403
Regulatory protein, TetR.
  
     0.595
CF8_1815
Hypothetical protein; Overlaps another CDS with the same product name.
  
     0.576
Your Current Organism:
Nocardioides sp. CF8
NCBI taxonomy Id: 110319
Other names: N. sp. CF8
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.