Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CF8_2827Hypothetical protein. (360 aa)    
Predicted Functional Partners:
CF8_2828
ferredoxin--NAD(+) reductase.
       0.773
CF8_2826
Protein of unknown function RIO1.
       0.762
CF8_0366
4Fe-4S ferredoxin iron-sulfur binding protein.
    
  0.627
CF8_1795
4Fe-4S ferredoxin iron-sulfur binding protein.
    
  0.627
CF8_2102
4Fe-4S ferredoxin iron-sulfur binding protein.
    
  0.627
dxr
1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.
       0.524
CF8_2822
Peptidase M50.
       0.523
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
   
 
  0.500
CF8_2824
propionate--CoA ligase.
       0.498
CF8_2825
Peptidase M1, membrane alanine aminopeptidase.
       0.487
Your Current Organism:
Nocardioides sp. CF8
NCBI taxonomy Id: 110319
Other names: N. sp. CF8
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