Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CF8_3330Mannose-6-phosphate isomerase, type II. (119 aa)    
Predicted Functional Partners:
CF8_2980
Mannose-1-phosphate guanylyltransferase (GDP).
  
  0.980
CF8_3177
Sugar transferase.
  
 
 0.916
CF8_3323
Sugar transferase.
  
 
 0.916
CF8_1186
Phosphomannomutase.
 
 
 0.865
CF8_3046
Phosphoglucomutase/phosphomannomutase.
  
 
 0.840
glmS
Glucosamine--fructose-6-phosphate; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
    
  0.817
CF8_0717
Ribokinase-like domain-containing protein.
    
 0.812
CF8_2801
PTS system, fructose subfamily, IIC subunit.
     
 0.812
CF8_3328
dTDP-4-keto-L-rhamnose reductase and; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.
  
 
 0.812
pfp
Pyrophosphate--fructose-6-phosphate; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
    
 0.811
Your Current Organism:
Nocardioides sp. CF8
NCBI taxonomy Id: 110319
Other names: N. sp. CF8
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