CF8_3531 protein (Nocardioides sp. CF8) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

CF8_3531

Sigma-70 region 4 domain-containing protein; Belongs to the sigma-70 factor family. (256 aa)

Predicted Functional Partners:

rpoB

0.952

rpoA

0.952

rpoC

0.949

rpoZ

0.938

CF8_1394

0.898

CF8_3392

0.841

sigA

0.766

CF8_2535

0.752

rpsO

0.658

CF8_3838

0.648

Your Current Organism:

Nocardioides sp. CF8

NCBI taxonomy Id: 110319
Other names: N. sp. CF8

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CF8_1394	CF8_3392	CF8_1394	CF8_3392	Anti-sigma factor.	ATPase domain-containing protein.	0.475
CF8_1394	CF8_3531	CF8_1394	CF8_3531	Anti-sigma factor.	Sigma-70 region 4 domain-containing protein; Belongs to the sigma-70 factor family.	0.898
CF8_2535	CF8_3531	CF8_2535	CF8_3531	Sigma-70 region 3 domain-containing protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	Sigma-70 region 4 domain-containing protein; Belongs to the sigma-70 factor family.	0.752
CF8_2535	CF8_3838	CF8_2535	CF8_3838	Sigma-70 region 3 domain-containing protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	Hypothetical protein; Belongs to the sigma-70 factor family. ECF subfamily.	0.515
CF8_2535	rpoA	CF8_2535	CF8_0714	Sigma-70 region 3 domain-containing protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.978
CF8_2535	rpoB	CF8_2535	CF8_0545	Sigma-70 region 3 domain-containing protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.983
CF8_2535	rpoC	CF8_2535	CF8_0546	Sigma-70 region 3 domain-containing protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.970
CF8_2535	rpoZ	CF8_2535	CF8_2292	Sigma-70 region 3 domain-containing protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	0.956
CF8_2535	sigA	CF8_2535	CF8_2542	Sigma-70 region 3 domain-containing protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.	0.704
CF8_3392	CF8_1394	CF8_3392	CF8_1394	ATPase domain-containing protein.	Anti-sigma factor.	0.475
CF8_3392	CF8_3531	CF8_3392	CF8_3531	ATPase domain-containing protein.	Sigma-70 region 4 domain-containing protein; Belongs to the sigma-70 factor family.	0.841
CF8_3531	CF8_1394	CF8_3531	CF8_1394	Sigma-70 region 4 domain-containing protein; Belongs to the sigma-70 factor family.	Anti-sigma factor.	0.898
CF8_3531	CF8_2535	CF8_3531	CF8_2535	Sigma-70 region 4 domain-containing protein; Belongs to the sigma-70 factor family.	Sigma-70 region 3 domain-containing protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	0.752
CF8_3531	CF8_3392	CF8_3531	CF8_3392	Sigma-70 region 4 domain-containing protein; Belongs to the sigma-70 factor family.	ATPase domain-containing protein.	0.841
CF8_3531	CF8_3838	CF8_3531	CF8_3838	Sigma-70 region 4 domain-containing protein; Belongs to the sigma-70 factor family.	Hypothetical protein; Belongs to the sigma-70 factor family. ECF subfamily.	0.648
CF8_3531	rpoA	CF8_3531	CF8_0714	Sigma-70 region 4 domain-containing protein; Belongs to the sigma-70 factor family.	DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.952
CF8_3531	rpoB	CF8_3531	CF8_0545	Sigma-70 region 4 domain-containing protein; Belongs to the sigma-70 factor family.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.952
CF8_3531	rpoC	CF8_3531	CF8_0546	Sigma-70 region 4 domain-containing protein; Belongs to the sigma-70 factor family.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.949
CF8_3531	rpoZ	CF8_3531	CF8_2292	Sigma-70 region 4 domain-containing protein; Belongs to the sigma-70 factor family.	DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	0.938
CF8_3531	rpsO	CF8_3531	CF8_2791	Sigma-70 region 4 domain-containing protein; Belongs to the sigma-70 factor family.	SSU ribosomal protein S15P; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.	0.658