Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CF8_3598Dehydrogenase catalytic domain-containing. (511 aa)    
Predicted Functional Partners:
CF8_3599
Transketolase, central region.
 
 0.999
CF8_3600
Pyruvate dehydrogenase (acetyl-transferring).
 
 0.998
CF8_1408
Alpha-ketoglutarate decarboxylase.
 
0.996
CF8_2429
Dihydrolipoamide dehydrogenase.
 0.996
CF8_3032
Dihydrolipoamide dehydrogenase.
 0.995
CF8_3031
Flavoprotein disulfide reductase.
 0.984
CF8_2266
FAD-dependent pyridine nucleotide-disulfide.
 0.980
CF8_1147
Pyruvate dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.978
sucC
succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 0.969
CF8_0737
Citrate synthase; Belongs to the citrate synthase family.
 
 0.932
Your Current Organism:
Nocardioides sp. CF8
NCBI taxonomy Id: 110319
Other names: N. sp. CF8
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