CF8_3750 protein (Nocardioides sp. CF8) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

CF8_3750

Putative suppressor protein DnaK. (143 aa)

Predicted Functional Partners:

rpoB

0.758

rpoC

0.757

rpoZ

0.680

rpoA

0.664

mraY-2

0.597

CF8_1321

0.586

CF8_3398

0.524

CF8_2535

0.496

sigA

0.496

rplU

0.416

Your Current Organism:

Nocardioides sp. CF8

NCBI taxonomy Id: 110319
Other names: N. sp. CF8

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CF8_1321	CF8_3750	CF8_1321	CF8_3750	Cobalamin synthesis CobW domain protein.	Putative suppressor protein DnaK.	0.586
CF8_2535	CF8_3398	CF8_2535	CF8_3398	Sigma-70 region 3 domain-containing protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	Hypothetical protein.	0.542
CF8_2535	CF8_3750	CF8_2535	CF8_3750	Sigma-70 region 3 domain-containing protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	Putative suppressor protein DnaK.	0.496
CF8_2535	rpoA	CF8_2535	CF8_0714	Sigma-70 region 3 domain-containing protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.978
CF8_2535	rpoB	CF8_2535	CF8_0545	Sigma-70 region 3 domain-containing protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.983
CF8_2535	rpoC	CF8_2535	CF8_0546	Sigma-70 region 3 domain-containing protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.970
CF8_2535	rpoZ	CF8_2535	CF8_2292	Sigma-70 region 3 domain-containing protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	0.956
CF8_2535	sigA	CF8_2535	CF8_2542	Sigma-70 region 3 domain-containing protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.	0.704
CF8_3398	CF8_2535	CF8_3398	CF8_2535	Hypothetical protein.	Sigma-70 region 3 domain-containing protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	0.542
CF8_3398	CF8_3750	CF8_3398	CF8_3750	Hypothetical protein.	Putative suppressor protein DnaK.	0.524
CF8_3398	sigA	CF8_3398	CF8_2542	Hypothetical protein.	RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.	0.542
CF8_3750	CF8_1321	CF8_3750	CF8_1321	Putative suppressor protein DnaK.	Cobalamin synthesis CobW domain protein.	0.586
CF8_3750	CF8_2535	CF8_3750	CF8_2535	Putative suppressor protein DnaK.	Sigma-70 region 3 domain-containing protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	0.496
CF8_3750	CF8_3398	CF8_3750	CF8_3398	Putative suppressor protein DnaK.	Hypothetical protein.	0.524
CF8_3750	mraY-2	CF8_3750	CF8_3751	Putative suppressor protein DnaK.	phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.	0.597
CF8_3750	rplU	CF8_3750	CF8_1121	Putative suppressor protein DnaK.	50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.	0.416
CF8_3750	rpoA	CF8_3750	CF8_0714	Putative suppressor protein DnaK.	DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.664
CF8_3750	rpoB	CF8_3750	CF8_0545	Putative suppressor protein DnaK.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.758
CF8_3750	rpoC	CF8_3750	CF8_0546	Putative suppressor protein DnaK.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.757
CF8_3750	rpoZ	CF8_3750	CF8_2292	Putative suppressor protein DnaK.	DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	0.680