Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CF8_3953Chromosomal replication initiator DnaA. (236 aa)    
Predicted Functional Partners:
CF8_3797
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 0.981
CF8_4042
Phosphoheptose isomerase.
    
 0.858
CF8_0529
DnaB domain protein helicase domain protein.
   
 0.803
CF8_0531
DnaB domain protein helicase domain protein.
   
 0.803
CF8_3757
DnaB domain-containing protein; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
   
 0.803
CF8_1250
UvrD/REP helicase.
   
 
 0.791
CF8_1645
Nucleoid protein Hbs; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
    
 0.780
CF8_2896
Nucleoid protein Hbs; Belongs to the bacterial histone-like protein family.
    
 0.780
CF8_3952
Hypothetical protein.
       0.773
CF8_4041
Sedoheptulose 7-phosphate isomerase.
    
  0.753
Your Current Organism:
Nocardioides sp. CF8
NCBI taxonomy Id: 110319
Other names: N. sp. CF8
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