Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-expression
Experiments
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[Homology]
Score
CF8_4022Hypothetical protein. (303 aa)    
Predicted Functional Partners:
CF8_4021
HpcH/HpaI aldolase; Belongs to the HpcH/HpaI aldolase family.
 
 
 0.940
CF8_3518
HpcH/HpaI aldolase; Belongs to the HpcH/HpaI aldolase family.
  
 
 0.840
CF8_4018
Formyl-CoA transferase; Belongs to the CoA-transferase III family.
 
 
  0.838
CF8_4020
acyl-CoA dehydrogenase domain-containing.
 
     0.804
CF8_3519
Citryl-CoA lyase; Belongs to the HpcH/HpaI aldolase family.
 
 
 0.780
CF8_4019
MmgE/PrpD.
 
  
 0.775
sucD
succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
   
 
  0.687
sucC
succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
   
 
  0.684
CF8_4014
3-hydroxyisobutyrate dehydrogenase.
 
     0.588
CF8_0944
Hypothetical protein.
  
  
  0.582
Your Current Organism:
Nocardioides sp. CF8
NCBI taxonomy Id: 110319
Other names: N. sp. CF8
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