Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
CF8_4034Hydrogenase-2, large subunit. (545 aa)    
Predicted Functional Partners:
CF8_4033
Hydrogenase (NiFe) small subunit HydA.
 
 0.999
CF8_4035
Hydrogenase maturation protease.
 
 0.986
hypA
Hydrogenase nickel incorporation protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.970
CF8_4036
TPR repeat-containing protein.
 
     0.957
CF8_4037
Nitrogen-fixing NifU domain-containing protein.
 
   
 0.947
CF8_4040
Hydrogenase assembly chaperone hypC/hupF.
 
 
 0.944
CF8_4039
NiFe hydrogenase maturation protein.
 
 
 
 0.943
CF8_4045
Hydrogenase expression/formation protein HypD.
 
 
 0.938
CF8_4038
NHL repeat-containing protein.
 
     0.937
CF8_4043
Hydrogenase expression/formation protein HypE.
 
   
 0.929
Your Current Organism:
Nocardioides sp. CF8
NCBI taxonomy Id: 110319
Other names: N. sp. CF8
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