node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EJF38238.1 | larC | HMPREF1141_3375 | HMPREF1141_2338 | 4Fe-4S binding domain protein. | TIGR00299 family protein; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family. | 0.456 |
EJF40735.1 | EJF40963.1 | HMPREF1141_1223 | HMPREF1141_2337 | Phosphoribosylaminoimidazole carboxylase. | TIGR00268 family protein; This gene contains a nucleotide ambiguity which may be the result of a sequencing error. | 0.971 |
EJF40735.1 | EJF41860.1 | HMPREF1141_1223 | HMPREF1141_1397 | Phosphoribosylaminoimidazole carboxylase. | PF09861 family protein. | 0.913 |
EJF40735.1 | cinA | HMPREF1141_1223 | HMPREF1141_0465 | Phosphoribosylaminoimidazole carboxylase. | Competence/damage-inducible protein CinA; Belongs to the CinA family. | 0.441 |
EJF40735.1 | guaA | HMPREF1141_1223 | HMPREF1141_0543 | Phosphoribosylaminoimidazole carboxylase. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.465 |
EJF40735.1 | larC | HMPREF1141_1223 | HMPREF1141_2338 | Phosphoribosylaminoimidazole carboxylase. | TIGR00299 family protein; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family. | 0.957 |
EJF40958.1 | EJF40963.1 | HMPREF1141_2339 | HMPREF1141_2337 | Hypothetical protein; Identified by glimmer; putative. | TIGR00268 family protein; This gene contains a nucleotide ambiguity which may be the result of a sequencing error. | 0.716 |
EJF40958.1 | larC | HMPREF1141_2339 | HMPREF1141_2338 | Hypothetical protein; Identified by glimmer; putative. | TIGR00299 family protein; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family. | 0.741 |
EJF40963.1 | EJF40735.1 | HMPREF1141_2337 | HMPREF1141_1223 | TIGR00268 family protein; This gene contains a nucleotide ambiguity which may be the result of a sequencing error. | Phosphoribosylaminoimidazole carboxylase. | 0.971 |
EJF40963.1 | EJF40958.1 | HMPREF1141_2337 | HMPREF1141_2339 | TIGR00268 family protein; This gene contains a nucleotide ambiguity which may be the result of a sequencing error. | Hypothetical protein; Identified by glimmer; putative. | 0.716 |
EJF40963.1 | EJF41860.1 | HMPREF1141_2337 | HMPREF1141_1397 | TIGR00268 family protein; This gene contains a nucleotide ambiguity which may be the result of a sequencing error. | PF09861 family protein. | 0.874 |
EJF40963.1 | guaA | HMPREF1141_2337 | HMPREF1141_0543 | TIGR00268 family protein; This gene contains a nucleotide ambiguity which may be the result of a sequencing error. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.441 |
EJF40963.1 | larC | HMPREF1141_2337 | HMPREF1141_2338 | TIGR00268 family protein; This gene contains a nucleotide ambiguity which may be the result of a sequencing error. | TIGR00299 family protein; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family. | 0.990 |
EJF41860.1 | EJF40735.1 | HMPREF1141_1397 | HMPREF1141_1223 | PF09861 family protein. | Phosphoribosylaminoimidazole carboxylase. | 0.913 |
EJF41860.1 | EJF40963.1 | HMPREF1141_1397 | HMPREF1141_2337 | PF09861 family protein. | TIGR00268 family protein; This gene contains a nucleotide ambiguity which may be the result of a sequencing error. | 0.874 |
EJF41860.1 | larC | HMPREF1141_1397 | HMPREF1141_2338 | PF09861 family protein. | TIGR00299 family protein; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family. | 0.814 |
cinA | EJF40735.1 | HMPREF1141_0465 | HMPREF1141_1223 | Competence/damage-inducible protein CinA; Belongs to the CinA family. | Phosphoribosylaminoimidazole carboxylase. | 0.441 |
cinA | guaA | HMPREF1141_0465 | HMPREF1141_0543 | Competence/damage-inducible protein CinA; Belongs to the CinA family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.510 |
cinA | larC | HMPREF1141_0465 | HMPREF1141_2338 | Competence/damage-inducible protein CinA; Belongs to the CinA family. | TIGR00299 family protein; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family. | 0.441 |
guaA | EJF40735.1 | HMPREF1141_0543 | HMPREF1141_1223 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Phosphoribosylaminoimidazole carboxylase. | 0.465 |