Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
KMV24094.1GTP pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (285 aa)    
Predicted Functional Partners:
KMV21881.1
GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
    
 0.841
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
     
  0.774
KMV24095.1
Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
     
 0.751
KMV24096.1
Cytochrome P450; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cytochrome P450 family.
       0.747
KMV24097.1
C4-dicarboxylate ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.747
KMV23246.1
Amino acid-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.643
KMV24500.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.606
KMV21171.1
Exopolyphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.606
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
     
  0.530
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
     
 0.510
Your Current Organism:
Mycobacterium heckeshornense
NCBI taxonomy Id: 110505
Other names: CCUG 51897, CIP 107347, DSM 44428, JCM 15655, M. heckeshornense, Mycobacterium heckeshornense Roth et al. 2001, strain S369
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