Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KMV23164.1Phosphoheptose isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (220 aa)    
Predicted Functional Partners:
KMV23165.1
Hydrogenase assembly protein HupF; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.936
hypF
Hydrogenase maturation protein HypF; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.864
KMV23162.1
Hydrogenase formation protein HupD; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.790
KMV23244.1
Hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.790
hypC
Hydrogenase assembly protein HupF; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.785
KMV23161.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.784
mshA
Diguanylate cyclase; Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2- deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
    
 0.746
dnaA
Chromosomal replication initiation protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
    
 
 0.695
KMV23171.1
Hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.694
KMV23172.1
Hydrogenase expression protein HypE; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.662
Your Current Organism:
Mycobacterium heckeshornense
NCBI taxonomy Id: 110505
Other names: CCUG 51897, CIP 107347, DSM 44428, JCM 15655, M. heckeshornense, Mycobacterium heckeshornense Roth et al. 2001, strain S369
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.