Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hypBHydrogenase expression protein HupH; Derived by automated computational analysis using gene prediction method: Protein Homology. (258 aa)    
Predicted Functional Partners:
hypA
Hydrogenase expression protein HupH; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 0.995
hypC-2
Hydantoin utilization protein C; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.969
KMV23162.1
Hydrogenase formation protein HupD; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.963
hypC
Hydrogenase assembly protein HupF; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.923
hypF
Hydrogenase maturation protein HypF; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.900
KMV23214.1
Peptidase M52; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.886
KMV23244.1
Hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.883
KMV19723.1
NADH-ubiquinone oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.812
KMV23172.1
Hydrogenase expression protein HypE; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.717
KMV23171.1
Hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.586
Your Current Organism:
Mycobacterium heckeshornense
NCBI taxonomy Id: 110505
Other names: CCUG 51897, CIP 107347, DSM 44428, JCM 15655, M. heckeshornense, Mycobacterium heckeshornense Roth et al. 2001, strain S369
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