Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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[Homology]
Score
KMV23084.1YVTN beta-propeller repeat-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (384 aa)    
Predicted Functional Partners:
KMV18057.1
Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.836
KMV23388.1
Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.788
KMV21069.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
 0.662
KMV21070.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.662
KMV15091.1
Nitric oxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.662
KMV21636.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.590
nadE
NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
 
  
  0.575
guaB
Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.573
KMV18071.1
Menaquinol-cytochrome C reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.546
purD
Phosphoribosylamine--glycine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GARS family.
    
  0.544
Your Current Organism:
Mycobacterium heckeshornense
NCBI taxonomy Id: 110505
Other names: CCUG 51897, CIP 107347, DSM 44428, JCM 15655, M. heckeshornense, Mycobacterium heckeshornense Roth et al. 2001, strain S369
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