Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KMV23103.1Isochorismatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (210 aa)    
Predicted Functional Partners:
KMV13610.1
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.635
KMV23062.1
Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.623
KMV22455.1
Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.621
KMV22717.1
Isochorismate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.568
KMV21578.1
Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.552
KMV23061.1
Luciferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
  0.548
KMV22685.1
Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.514
KMV22625.1
Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.508
nnrD
Membrane protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers [...]
  
    0.501
gcvT
Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine.
   
 
 0.482
Your Current Organism:
Mycobacterium heckeshornense
NCBI taxonomy Id: 110505
Other names: CCUG 51897, CIP 107347, DSM 44428, JCM 15655, M. heckeshornense, Mycobacterium heckeshornense Roth et al. 2001, strain S369
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.