Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pxpAHypothetical protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. (252 aa)    
Predicted Functional Partners:
KMV23553.1
Allophanate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.994
KMV23552.1
Allophanate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.975
KMV24412.1
Carboxylate--amine ligase; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
     
  0.921
KMV24086.1
Acylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.900
egtA
Glutamate--cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine.
     
  0.900
KMV22839.1
Metallo-beta-lactamase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.855
KMV23011.1
Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family.
   
 
  0.803
KMV21563.1
Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family.
   
 
  0.803
glnA
Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.803
KMV20989.1
NAD-glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.803
Your Current Organism:
Mycobacterium heckeshornense
NCBI taxonomy Id: 110505
Other names: CCUG 51897, CIP 107347, DSM 44428, JCM 15655, M. heckeshornense, Mycobacterium heckeshornense Roth et al. 2001, strain S369
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