Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KMV22689.15,10-methylene tetrahydromethanopterin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (265 aa)    
Predicted Functional Partners:
KMV22638.1
Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.880
fgd
Glucose-6-phosphate dehydrogenase; Catalyzes the coenzyme F420-dependent oxidation of glucose 6- phosphate (G6P) to 6-phosphogluconolactone. Appears to have a role in resistance to oxidative stress, via its consumption of G6P that serves as a source of reducing power to combat oxidative stress in mycobacteria.
  
   
 0.778
KMV22869.1
Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.756
KMV22640.1
Amino acid ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.752
KMV22317.1
Nitroreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.752
KMV17223.1
Nitroreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.751
KMV21823.1
Deazaflavin-dependent nitroreductase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.744
KMV22639.1
GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.737
KMV22637.1
Inositol-3-phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.728
KMV22641.1
MarR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.719
Your Current Organism:
Mycobacterium heckeshornense
NCBI taxonomy Id: 110505
Other names: CCUG 51897, CIP 107347, DSM 44428, JCM 15655, M. heckeshornense, Mycobacterium heckeshornense Roth et al. 2001, strain S369
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