Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KMV22526.1Glutamate--cysteine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (499 aa)    
Predicted Functional Partners:
egtB
iron(II)-dependent oxidoreductase EgtB; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family.
  
 
 0.905
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
       0.711
KMV23689.1
Sulfatase-modifying factor 1; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.595
KMV22261.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.589
ddl
D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
    
  0.537
KMV18065.1
Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.434
KMV23874.1
Stage II sporulation protein E; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.423
KMV24507.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.414
Your Current Organism:
Mycobacterium heckeshornense
NCBI taxonomy Id: 110505
Other names: CCUG 51897, CIP 107347, DSM 44428, JCM 15655, M. heckeshornense, Mycobacterium heckeshornense Roth et al. 2001, strain S369
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