STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KMV22112.1Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1768 aa)    
Predicted Functional Partners:
KMV22083.1
Exonuclease V subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.803
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
    
 
 0.793
KMV21772.1
LtrC; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.612
KMV22113.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the N(4)/N(6)-methyltransferase family.
 
   
 0.575
KMV14311.1
Integrase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.559
KMV13468.1
Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.522
KMV15621.1
Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.521
KMV13567.1
PPE family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.515
KMV13550.1
Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.508
KMV22098.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.485
Your Current Organism:
Mycobacterium heckeshornense
NCBI taxonomy Id: 110505
Other names: CCUG 51897, CIP 107347, DSM 44428, JCM 15655, M. heckeshornense, Mycobacterium heckeshornense Roth et al. 2001, strain S369
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.