Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KMV21934.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (160 aa)    
Predicted Functional Partners:
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
       0.713
hisE
phosphoribosyl-ATP pyrophosphatase; Catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.664
KMV24367.1
1,4-beta-xylanase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 5 (cellulase A) family.
  
     0.594
KMV23229.1
1,4-beta-xylanase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.591
KMV21932.1
Major facilitator transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
       0.565
KMV22960.1
1,3-beta-glucanase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.510
metH
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
       0.472
KMV22516.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.464
eccD-3
Secretion protein EccD; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.440
KMV22445.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.437
Your Current Organism:
Mycobacterium heckeshornense
NCBI taxonomy Id: 110505
Other names: CCUG 51897, CIP 107347, DSM 44428, JCM 15655, M. heckeshornense, Mycobacterium heckeshornense Roth et al. 2001, strain S369
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