Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
KMV21635.1Fe-S cluster assembly protein HesB; Derived by automated computational analysis using gene prediction method: Protein Homology. (199 aa)    
Predicted Functional Partners:
KMV23727.1
Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.773
KMV21633.1
Pyridoxine 5'-phosphate oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.604
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 
 0.582
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
  
  
 0.576
KMV21145.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.545
KMV21954.1
5'-3' exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.534
ligC
ATP-dependent DNA ligase; Catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA; in mycobacteria LigC has weak intrinsic nick joining activities and is not essential for growth; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.531
KMV21634.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.521
KMV21667.1
Pyridoxamine 5-phosphate oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.513
KMV22277.1
HNH nuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.474
Your Current Organism:
Mycobacterium heckeshornense
NCBI taxonomy Id: 110505
Other names: CCUG 51897, CIP 107347, DSM 44428, JCM 15655, M. heckeshornense, Mycobacterium heckeshornense Roth et al. 2001, strain S369
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