Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KMV21420.1Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (291 aa)    
Predicted Functional Partners:
KMV21474.1
Patatin; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.882
KMV21419.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.834
KMV21418.1
Long-chain fatty acid--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.745
KMV21417.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.702
egtB
iron(II)-dependent oxidoreductase EgtB; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family.
  
 
 0.631
KMV23689.1
Sulfatase-modifying factor 1; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.630
egtD
histidyl-tRNA synthetase; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family.
  
  
 0.615
KMV22268.1
Cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
  
 
 0.576
KMV22010.1
Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.576
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
     
  0.522
Your Current Organism:
Mycobacterium heckeshornense
NCBI taxonomy Id: 110505
Other names: CCUG 51897, CIP 107347, DSM 44428, JCM 15655, M. heckeshornense, Mycobacterium heckeshornense Roth et al. 2001, strain S369
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