Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
KMV21477.1Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (269 aa)    
Predicted Functional Partners:
KMV21464.1
Guanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.705
zwf-3
Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
       0.688
gnd
6-phosphogluconate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.682
KMV23948.1
Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.669
KMV21002.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.653
KMV22568.1
Adenylyl cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.635
KMV23874.1
Stage II sporulation protein E; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.594
KMV21687.1
Adenylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
 
 
 0.580
KMV21282.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.554
htpG
Heat shock protein 90; Molecular chaperone. Has ATPase activity.
  
 
 0.501
Your Current Organism:
Mycobacterium heckeshornense
NCBI taxonomy Id: 110505
Other names: CCUG 51897, CIP 107347, DSM 44428, JCM 15655, M. heckeshornense, Mycobacterium heckeshornense Roth et al. 2001, strain S369
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