Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KMV21285.1ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (291 aa)    
Predicted Functional Partners:
KMV21286.1
Von Willebrand factor A; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.966
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
       0.845
KMV22798.1
Nitric oxide reductase activation protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.732
KMV21281.1
Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.635
KMV24330.1
Carbon monoxide dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.607
KMV24331.1
Xanthine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.595
KMV24329.1
Carbon monoxide dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.577
KMV21283.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.540
KMV21282.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.519
rbsK
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
       0.488
Your Current Organism:
Mycobacterium heckeshornense
NCBI taxonomy Id: 110505
Other names: CCUG 51897, CIP 107347, DSM 44428, JCM 15655, M. heckeshornense, Mycobacterium heckeshornense Roth et al. 2001, strain S369
Server load: low (30%) [HD]