| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KMV22462.1 | clpP | ACT16_11575 | ACT16_19025 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Clp protease; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.728 |
| KMV22462.1 | clpP-2 | ACT16_11575 | ACT16_19030 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Clp protease ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.728 |
| KMV22462.1 | clpX | ACT16_11575 | ACT16_19015 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | ATP-dependent protease; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.815 |
| KMV23874.1 | atpD | ACT16_03125 | ACT16_12110 | Stage II sporulation protein E; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP F0F1 synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. | 0.558 |
| KMV23874.1 | clpP | ACT16_03125 | ACT16_19025 | Stage II sporulation protein E; Derived by automated computational analysis using gene prediction method: Protein Homology. | Clp protease; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.830 |
| KMV23874.1 | clpP-2 | ACT16_03125 | ACT16_19030 | Stage II sporulation protein E; Derived by automated computational analysis using gene prediction method: Protein Homology. | Clp protease ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.830 |
| KMV23874.1 | clpX | ACT16_03125 | ACT16_19015 | Stage II sporulation protein E; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent protease; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.834 |
| KMV23874.1 | dnaK | ACT16_03125 | ACT16_00115 | Stage II sporulation protein E; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.666 |
| KMV23874.1 | ftsH | ACT16_03125 | ACT16_08685 | Stage II sporulation protein E; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.714 |
| KMV23874.1 | groEL | ACT16_03125 | ACT16_00610 | Stage II sporulation protein E; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.768 |
| KMV23874.1 | groEL-2 | ACT16_03125 | ACT16_04090 | Stage II sporulation protein E; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.768 |
| KMV23874.1 | groS | ACT16_03125 | ACT16_04095 | Stage II sporulation protein E; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.697 |
| atpD | KMV23874.1 | ACT16_12110 | ACT16_03125 | ATP F0F1 synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. | Stage II sporulation protein E; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.558 |
| atpD | clpP | ACT16_12110 | ACT16_19025 | ATP F0F1 synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. | Clp protease; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.550 |
| atpD | clpP-2 | ACT16_12110 | ACT16_19030 | ATP F0F1 synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. | Clp protease ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.550 |
| atpD | clpX | ACT16_12110 | ACT16_19015 | ATP F0F1 synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. | ATP-dependent protease; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.845 |
| atpD | dnaK | ACT16_12110 | ACT16_00115 | ATP F0F1 synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.678 |
| atpD | ftsH | ACT16_12110 | ACT16_08685 | ATP F0F1 synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. | Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.590 |
| atpD | groEL | ACT16_12110 | ACT16_00610 | ATP F0F1 synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. | Molecular chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.685 |
| atpD | groEL-2 | ACT16_12110 | ACT16_04090 | ATP F0F1 synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. | Molecular chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.685 |
