Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KMV20929.13-methyladenine DNA glycosylase; Constitutive, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine; Derived by automated computational analysis using gene prediction method: Protein Homology. (187 aa)    
Predicted Functional Partners:
KMV20928.1
Cell division protein DivIVA; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.855
folP-2
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
  
    0.783
KMV20927.1
Glucosyl-3-phosphoglycerate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.781
KMV21000.1
Cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
   
 0.768
KMV20926.1
long-chain-acyl-CoA synthetase; Activates fatty acids by binding to coenzyme A; may be involved in acyclic terpene utilization; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.747
KMV20936.1
ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.592
KMV20925.1
Decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LOG family.
       0.575
KMV23086.1
Damage-inducible protein CinA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family.
  
    0.523
KMV21001.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.501
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.468
Your Current Organism:
Mycobacterium heckeshornense
NCBI taxonomy Id: 110505
Other names: CCUG 51897, CIP 107347, DSM 44428, JCM 15655, M. heckeshornense, Mycobacterium heckeshornense Roth et al. 2001, strain S369
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