Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KMV18224.1Metallophosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (319 aa)    
Predicted Functional Partners:
KMV18225.1
4'-phosphopantetheinyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the P-Pant transferase superfamily.
 
  
 0.956
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
       0.855
KMV18227.1
Lipid-transfer protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family.
       0.818
KMV18223.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.729
KMV13610.1
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.583
KMV20869.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
  
 0.576
KMV17722.1
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.574
KMV21995.1
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.555
KMV14801.1
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.543
ppnK
Inorganic polyphosphate kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
    
  0.522
Your Current Organism:
Mycobacterium heckeshornense
NCBI taxonomy Id: 110505
Other names: CCUG 51897, CIP 107347, DSM 44428, JCM 15655, M. heckeshornense, Mycobacterium heckeshornense Roth et al. 2001, strain S369
Server load: low (14%) [HD]