MCE_00240 protein (Rickettsia amblyommatis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

MCE_00240

COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32). (374 aa)

Predicted Functional Partners:

MCE_00235

0.984

dnaG

0.908

rpoB

0.885

rpoA

0.875

rpoC

0.872

MCE_04810

0.869

nusA

0.853

rpoZ

0.840

MCE_00775

0.832

MCE_04310

0.816

Your Current Organism:

Rickettsia amblyommatis

NCBI taxonomy Id: 1105111
Other names: Candidatus Rickettsia amblyommii str. GAT-30V, R. amblyommatis str. GAT-30V, Rickettsia amblyommatis str. GAT-30V

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MCE_00235	MCE_00240	MCE_00235	MCE_00240	RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32).	0.984
MCE_00235	MCE_00775	MCE_00235	MCE_00775	RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	COG1329 Transcriptional regulators, similar to M. xanthus CarD.	0.809
MCE_00235	MCE_04310	MCE_00235	MCE_04310	RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	COG0625 Glutathione S-transferase.	0.787
MCE_00235	MCE_04810	MCE_00235	MCE_04810	RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	COG0350 Methylated DNA-protein cysteine methyltransferase.	0.869
MCE_00235	dnaG	MCE_00235	MCE_00245	RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.	0.951
MCE_00235	nusA	MCE_00235	MCE_05075	RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	Transcription elongation factor NusA; Participates in both transcription termination and antitermination.	0.805
MCE_00235	rpoA	MCE_00235	MCE_06465	RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.854
MCE_00235	rpoB	MCE_00235	MCE_01545	RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.885
MCE_00235	rpoC	MCE_00235	MCE_01550	RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.852
MCE_00235	rpoZ	MCE_00235	MCE_04730	RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	0.840
MCE_00240	MCE_00235	MCE_00240	MCE_00235	COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32).	RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	0.984
MCE_00240	MCE_00775	MCE_00240	MCE_00775	COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32).	COG1329 Transcriptional regulators, similar to M. xanthus CarD.	0.832
MCE_00240	MCE_04310	MCE_00240	MCE_04310	COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32).	COG0625 Glutathione S-transferase.	0.816
MCE_00240	MCE_04810	MCE_00240	MCE_04810	COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32).	COG0350 Methylated DNA-protein cysteine methyltransferase.	0.869
MCE_00240	dnaG	MCE_00240	MCE_00245	COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32).	DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.	0.908
MCE_00240	nusA	MCE_00240	MCE_05075	COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32).	Transcription elongation factor NusA; Participates in both transcription termination and antitermination.	0.853
MCE_00240	rpoA	MCE_00240	MCE_06465	COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32).	DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.875
MCE_00240	rpoB	MCE_00240	MCE_01545	COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32).	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.885
MCE_00240	rpoC	MCE_00240	MCE_01550	COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32).	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.872
MCE_00240	rpoZ	MCE_00240	MCE_04730	COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32).	DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	0.840