MCE_01480 protein (Rickettsia amblyommatis) - STRING interaction network

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Score

MCE_01480

COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit. (124 aa)

Predicted Functional Partners:

sdhB

0.999

MCE_01485

0.999

sdhA

0.999

sucC

0.994

sucD

0.989

fumC

0.976

nuoD

0.957

nuoI

0.950

MCE_03265

0.940

sucA

0.936

Your Current Organism:

Rickettsia amblyommatis

NCBI taxonomy Id: 1105111
Other names: Candidatus Rickettsia amblyommii str. GAT-30V, R. amblyommatis str. GAT-30V, Rickettsia amblyommatis str. GAT-30V

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MCE_01480	MCE_01485	MCE_01480	MCE_01485	COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit.	COG2142 Succinate dehydrogenase, hydrophobic anchor subunit.	0.999
MCE_01480	MCE_03265	MCE_01480	MCE_03265	COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit.	COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit.	0.940
MCE_01480	fumC	MCE_01480	MCE_06610	COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit.	Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	0.976
MCE_01480	nuoD	MCE_01480	MCE_03275	COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit.	NADH dehydrogenase subunit D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.	0.957
MCE_01480	nuoI	MCE_01480	MCE_07745	COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit.	NADH dehydrogenase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.	0.950
MCE_01480	sdhA	MCE_01480	MCE_01490	COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit.	COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.	0.999
MCE_01480	sdhB	MCE_01480	MCE_00990	COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit.	COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.	0.999
MCE_01480	sucA	MCE_01480	MCE_01840	COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit.	COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes.	0.936
MCE_01480	sucC	MCE_01480	MCE_03880	COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit.	succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.994
MCE_01480	sucD	MCE_01480	MCE_03875	COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit.	succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	0.989
MCE_01485	MCE_01480	MCE_01485	MCE_01480	COG2142 Succinate dehydrogenase, hydrophobic anchor subunit.	COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit.	0.999
MCE_01485	fumC	MCE_01485	MCE_06610	COG2142 Succinate dehydrogenase, hydrophobic anchor subunit.	Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	0.922
MCE_01485	nuoD	MCE_01485	MCE_03275	COG2142 Succinate dehydrogenase, hydrophobic anchor subunit.	NADH dehydrogenase subunit D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.	0.636
MCE_01485	sdhA	MCE_01485	MCE_01490	COG2142 Succinate dehydrogenase, hydrophobic anchor subunit.	COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.	0.999
MCE_01485	sdhB	MCE_01485	MCE_00990	COG2142 Succinate dehydrogenase, hydrophobic anchor subunit.	COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.	0.999
MCE_01485	sucA	MCE_01485	MCE_01840	COG2142 Succinate dehydrogenase, hydrophobic anchor subunit.	COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes.	0.895
MCE_01485	sucC	MCE_01485	MCE_03880	COG2142 Succinate dehydrogenase, hydrophobic anchor subunit.	succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.990
MCE_01485	sucD	MCE_01485	MCE_03875	COG2142 Succinate dehydrogenase, hydrophobic anchor subunit.	succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	0.964
MCE_03265	MCE_01480	MCE_03265	MCE_01480	COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit.	COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit.	0.940
MCE_03265	fumC	MCE_03265	MCE_06610	COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit.	Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	0.402