| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MCE_00540 | MCE_01730 | MCE_00540 | MCE_01730 | Putative bifunctional glutamate synthase subunit beta/2-polyprenylphenol hydroxylase; COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases. | DNA-binding protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | 0.584 |
| MCE_00540 | MCE_07030 | MCE_00540 | MCE_07030 | Putative bifunctional glutamate synthase subunit beta/2-polyprenylphenol hydroxylase; COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases. | Integration host factor alpha-subunit; COG0776 Bacterial nucleoid DNA-binding protein; Belongs to the bacterial histone-like protein family. | 0.584 |
| MCE_01730 | MCE_00540 | MCE_01730 | MCE_00540 | DNA-binding protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | Putative bifunctional glutamate synthase subunit beta/2-polyprenylphenol hydroxylase; COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases. | 0.584 |
| MCE_01730 | MCE_06665 | MCE_01730 | MCE_06665 | DNA-binding protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | COG1278 Cold shock proteins. | 0.547 |
| MCE_01730 | MCE_07030 | MCE_01730 | MCE_07030 | DNA-binding protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | Integration host factor alpha-subunit; COG0776 Bacterial nucleoid DNA-binding protein; Belongs to the bacterial histone-like protein family. | 0.819 |
| MCE_01730 | MCE_07880 | MCE_01730 | MCE_07880 | DNA-binding protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | Glutathione-regulated potassium-efflux system protein; COG0475 Kef-type K+ transport systems, membrane components; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | 0.721 |
| MCE_01730 | dnaA | MCE_01730 | MCE_06105 | DNA-binding protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | Chromosomal replication initiation protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.550 |
| MCE_01730 | polA | MCE_01730 | MCE_07585 | DNA-binding protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.626 |
| MCE_01730 | rplS | MCE_01730 | MCE_01390 | DNA-binding protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | 50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.634 |
| MCE_01730 | rpsO | MCE_01730 | MCE_04235 | DNA-binding protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | 30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. | 0.638 |
| MCE_01730 | rpsT | MCE_01730 | MCE_06455 | DNA-binding protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | 30S ribosomal protein S20; Binds directly to 16S ribosomal RNA. | 0.655 |
| MCE_01730 | topA | MCE_01730 | MCE_03065 | DNA-binding protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.631 |
| MCE_06665 | MCE_01730 | MCE_06665 | MCE_01730 | COG1278 Cold shock proteins. | DNA-binding protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | 0.547 |
| MCE_06665 | MCE_07030 | MCE_06665 | MCE_07030 | COG1278 Cold shock proteins. | Integration host factor alpha-subunit; COG0776 Bacterial nucleoid DNA-binding protein; Belongs to the bacterial histone-like protein family. | 0.515 |
| MCE_06665 | MCE_07880 | MCE_06665 | MCE_07880 | COG1278 Cold shock proteins. | Glutathione-regulated potassium-efflux system protein; COG0475 Kef-type K+ transport systems, membrane components; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | 0.515 |
| MCE_06665 | polA | MCE_06665 | MCE_07585 | COG1278 Cold shock proteins. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.637 |
| MCE_06665 | rplS | MCE_06665 | MCE_01390 | COG1278 Cold shock proteins. | 50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.765 |
| MCE_06665 | rpsO | MCE_06665 | MCE_04235 | COG1278 Cold shock proteins. | 30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. | 0.618 |
| MCE_06665 | rpsT | MCE_06665 | MCE_06455 | COG1278 Cold shock proteins. | 30S ribosomal protein S20; Binds directly to 16S ribosomal RNA. | 0.663 |
| MCE_06665 | topA | MCE_06665 | MCE_03065 | COG1278 Cold shock proteins. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.425 |
STRING v12.5 is now available!
