MCE_01875 protein (Rickettsia amblyommatis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

MCE_01875

Heat shock protease; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain. (497 aa)

Predicted Functional Partners:

dnaK

0.774

MCE_04950

0.746

lon

0.699

alaS

0.679

MCE_04625

0.678

MCE_05825

0.670

fni

0.660

MCE_01380

0.651

MCE_07880

0.649

MCE_00835

0.635

Your Current Organism:

Rickettsia amblyommatis

NCBI taxonomy Id: 1105111
Other names: Candidatus Rickettsia amblyommii str. GAT-30V, R. amblyommatis str. GAT-30V, Rickettsia amblyommatis str. GAT-30V

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MCE_00835	MCE_01875	MCE_00835	MCE_01875	Hypothetical protein.	Heat shock protease; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.	0.635
MCE_00835	MCE_04625	MCE_00835	MCE_04625	Hypothetical protein.	COG0642 Signal transduction histidine kinase.	0.864
MCE_00835	MCE_04950	MCE_00835	MCE_04950	Hypothetical protein.	COG1250 3-hydroxyacyl-CoA dehydrogenase.	0.611
MCE_00835	MCE_05825	MCE_00835	MCE_05825	Hypothetical protein.	COG0642 Signal transduction histidine kinase.	0.864
MCE_00835	alaS	MCE_00835	MCE_00225	Hypothetical protein.	alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.	0.534
MCE_00835	dnaK	MCE_00835	MCE_01870	Hypothetical protein.	Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.942
MCE_01380	MCE_01875	MCE_01380	MCE_01875	Hypothetical protein.	Heat shock protease; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.	0.651
MCE_01875	MCE_00835	MCE_01875	MCE_00835	Heat shock protease; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.	Hypothetical protein.	0.635
MCE_01875	MCE_01380	MCE_01875	MCE_01380	Heat shock protease; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.	Hypothetical protein.	0.651
MCE_01875	MCE_04625	MCE_01875	MCE_04625	Heat shock protease; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.	COG0642 Signal transduction histidine kinase.	0.678
MCE_01875	MCE_04950	MCE_01875	MCE_04950	Heat shock protease; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.	COG1250 3-hydroxyacyl-CoA dehydrogenase.	0.746
MCE_01875	MCE_05825	MCE_01875	MCE_05825	Heat shock protease; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.	COG0642 Signal transduction histidine kinase.	0.670
MCE_01875	MCE_07880	MCE_01875	MCE_07880	Heat shock protease; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.	Glutathione-regulated potassium-efflux system protein; COG0475 Kef-type K+ transport systems, membrane components; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.	0.649
MCE_01875	alaS	MCE_01875	MCE_00225	Heat shock protease; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.	alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.	0.679
MCE_01875	dnaK	MCE_01875	MCE_01870	Heat shock protease; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.	Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.774
MCE_01875	fni	MCE_01875	MCE_05625	Heat shock protease; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.	Isopentenyl pyrophosphate isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).	0.660
MCE_01875	lon	MCE_01875	MCE_04065	Heat shock protease; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.	ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.	0.699
MCE_04625	MCE_00835	MCE_04625	MCE_00835	COG0642 Signal transduction histidine kinase.	Hypothetical protein.	0.864
MCE_04625	MCE_01875	MCE_04625	MCE_01875	COG0642 Signal transduction histidine kinase.	Heat shock protease; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.	0.678
MCE_04625	MCE_04950	MCE_04625	MCE_04950	COG0642 Signal transduction histidine kinase.	COG1250 3-hydroxyacyl-CoA dehydrogenase.	0.893

page 1 of 3

Server load: high (96%) [HD]

Permalink

Network

Neighborhood

Experiments

Cooccurrence

Databases

Coexpression

Textmining

Fusion

© STRING Consortium 2025

Credits

Access

Info

About