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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCE_02765COG3505 Type IV secretory pathway, VirD4 components. (591 aa)    
Predicted Functional Partners:
MCE_02755
virB10 protein; COG2948 Type IV secretory pathway, VirB10 components.
 
 
 
 0.964
MCE_02745
Hypothetical protein; COG3736 Type IV secretory pathway, component VirB8.
 
   
 0.911
MCE_02760
Type IV secretion system ATPase VirB11; Part of the Type IV secretion system. Belongs to the GSP E family.
 
   
 0.891
MCE_01175
COG3451 Type IV secretory pathway, VirB4 components.
 
  
 0.869
MCE_02730
VirB9; COG3504 Type IV secretory pathway, VirB9 components.
 
   
 0.865
MCE_01180
COG3702 Type IV secretory pathway, VirB3 components.
 
   
 0.860
MCE_02750
VirB9; COG3504 Type IV secretory pathway, VirB9 components.
 
   
 0.853
MCE_07675
VirB4; COG3451 Type IV secretory pathway, VirB4 components.
 
  
 0.817
MCE_02770
Guanosine pentaphosphate phosphohydrolase; COG0248 Exopolyphosphatase.
       0.782
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.536
Your Current Organism:
Rickettsia amblyommatis
NCBI taxonomy Id: 1105111
Other names: Candidatus Rickettsia amblyommii str. GAT-30V, R. amblyommatis str. GAT-30V, Rickettsia amblyommatis str. GAT-30V
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