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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCE_04015Succinate semialdehyde dehydrogenase; COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (499 aa)    
Predicted Functional Partners:
sdhA
COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
  
 0.962
gltA
COG0372 Citrate synthase; Belongs to the citrate synthase family.
  
 0.961
sdhB
COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
 
 0.947
fumC
Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
   
 0.919
MCE_01480
COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit.
  
 
  0.909
MCE_01485
COG2142 Succinate dehydrogenase, hydrophobic anchor subunit.
  
 
 0.907
sucA
COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes.
  
 
 0.894
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 0.894
MCE_02460
COG0473 Isocitrate/isopropylmalate dehydrogenase.
   
 0.890
MCE_04565
Hypothetical protein; COG0591 Na+/proline symporter.
  
 
 0.840
Your Current Organism:
Rickettsia amblyommatis
NCBI taxonomy Id: 1105111
Other names: Candidatus Rickettsia amblyommii str. GAT-30V, R. amblyommatis str. GAT-30V, Rickettsia amblyommatis str. GAT-30V
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