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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCE_04060COG1171 Threonine dehydratase. (344 aa)    
Predicted Functional Partners:
MCE_00835
Hypothetical protein.
  
 
 0.748
MCE_03855
COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase.
  
  
 0.722
MCE_00540
Putative bifunctional glutamate synthase subunit beta/2-polyprenylphenol hydroxylase; COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases.
  
 
 0.681
MCE_02460
COG0473 Isocitrate/isopropylmalate dehydrogenase.
 
  
 0.673
MCE_03415
COG0281 Malic enzyme.
  
 
 0.609
MCE_04950
COG1250 3-hydroxyacyl-CoA dehydrogenase.
  
 
 0.583
MCE_07400
COG0527 Aspartokinases; Belongs to the aspartokinase family.
  
 
 0.576
MCE_06315
Acylglycerophosphoethanolamine acyltransferase; COG0477 Permeases of the major facilitator superfamily.
     
 0.570
lon
ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
       0.551
MCE_02440
Pyruvate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
     
 0.534
Your Current Organism:
Rickettsia amblyommatis
NCBI taxonomy Id: 1105111
Other names: Candidatus Rickettsia amblyommii str. GAT-30V, R. amblyommatis str. GAT-30V, Rickettsia amblyommatis str. GAT-30V
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