MCE_04715 protein (Rickettsia amblyommatis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

MCE_04715

HAD family hydrolase; COG0647 Predicted sugar phosphatases of the HAD superfamily. (286 aa)

Predicted Functional Partners:

MCE_03415

0.557

MCE_03845

0.512

gyrB

0.456

cmk

0.449

MCE_07555

0.443

lspA

0.407

Your Current Organism:

Rickettsia amblyommatis

NCBI taxonomy Id: 1105111
Other names: Candidatus Rickettsia amblyommii str. GAT-30V, R. amblyommatis str. GAT-30V, Rickettsia amblyommatis str. GAT-30V

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MCE_03415	MCE_03845	MCE_03415	MCE_03845	COG0281 Malic enzyme.	Osmolarity sensor protein EnvZ; COG0642 Signal transduction histidine kinase.	0.545
MCE_03415	MCE_04715	MCE_03415	MCE_04715	COG0281 Malic enzyme.	HAD family hydrolase; COG0647 Predicted sugar phosphatases of the HAD superfamily.	0.557
MCE_03845	MCE_03415	MCE_03845	MCE_03415	Osmolarity sensor protein EnvZ; COG0642 Signal transduction histidine kinase.	COG0281 Malic enzyme.	0.545
MCE_03845	MCE_04715	MCE_03845	MCE_04715	Osmolarity sensor protein EnvZ; COG0642 Signal transduction histidine kinase.	HAD family hydrolase; COG0647 Predicted sugar phosphatases of the HAD superfamily.	0.512
MCE_03845	MCE_07555	MCE_03845	MCE_07555	Osmolarity sensor protein EnvZ; COG0642 Signal transduction histidine kinase.	COG0795 Predicted permeases.	0.522
MCE_04715	MCE_03415	MCE_04715	MCE_03415	HAD family hydrolase; COG0647 Predicted sugar phosphatases of the HAD superfamily.	COG0281 Malic enzyme.	0.557
MCE_04715	MCE_03845	MCE_04715	MCE_03845	HAD family hydrolase; COG0647 Predicted sugar phosphatases of the HAD superfamily.	Osmolarity sensor protein EnvZ; COG0642 Signal transduction histidine kinase.	0.512
MCE_04715	MCE_07555	MCE_04715	MCE_07555	HAD family hydrolase; COG0647 Predicted sugar phosphatases of the HAD superfamily.	COG0795 Predicted permeases.	0.443
MCE_04715	cmk	MCE_04715	MCE_05800	HAD family hydrolase; COG0647 Predicted sugar phosphatases of the HAD superfamily.	COG0283 Cytidylate kinase.	0.449
MCE_04715	gyrB	MCE_04715	MCE_04720	HAD family hydrolase; COG0647 Predicted sugar phosphatases of the HAD superfamily.	DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.	0.456
MCE_04715	lspA	MCE_04715	MCE_03695	HAD family hydrolase; COG0647 Predicted sugar phosphatases of the HAD superfamily.	Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.	0.407
MCE_07555	MCE_03845	MCE_07555	MCE_03845	COG0795 Predicted permeases.	Osmolarity sensor protein EnvZ; COG0642 Signal transduction histidine kinase.	0.522
MCE_07555	MCE_04715	MCE_07555	MCE_04715	COG0795 Predicted permeases.	HAD family hydrolase; COG0647 Predicted sugar phosphatases of the HAD superfamily.	0.443
cmk	MCE_04715	MCE_05800	MCE_04715	COG0283 Cytidylate kinase.	HAD family hydrolase; COG0647 Predicted sugar phosphatases of the HAD superfamily.	0.449
gyrB	MCE_04715	MCE_04720	MCE_04715	DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.	HAD family hydrolase; COG0647 Predicted sugar phosphatases of the HAD superfamily.	0.456
lspA	MCE_04715	MCE_03695	MCE_04715	Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.	HAD family hydrolase; COG0647 Predicted sugar phosphatases of the HAD superfamily.	0.407