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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCE_05840COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases. (235 aa)    
Predicted Functional Partners:
MCE_04605
COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases.
 
     0.976
MCE_06355
COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases.
 
     0.976
MCE_02770
Guanosine pentaphosphate phosphohydrolase; COG0248 Exopolyphosphatase.
  
 
 0.904
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
 
  0.903
ndk
Mulitfunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-phosphodiesterase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
  0.900
MCE_04160
Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
     
  0.900
nrdF
Ribonucleotide-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.
     
  0.900
MCE_07015
COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases.
 
     0.844
MCE_05835
COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases.
  
     0.735
MCE_01195
COG0254 Ribosomal protein L31; Belongs to the bacterial ribosomal protein bL31 family.
  
   0.493
Your Current Organism:
Rickettsia amblyommatis
NCBI taxonomy Id: 1105111
Other names: Candidatus Rickettsia amblyommii str. GAT-30V, R. amblyommatis str. GAT-30V, Rickettsia amblyommatis str. GAT-30V
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