Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MCE_05940Conjugal transfer protein TraA. (314 aa)    
Predicted Functional Partners:
MCE_07165
COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains).
  
 
 0.837
MCE_06015
Conjugal transfer protein TraA; COG0358 DNA primase (bacterial type).
 
     0.712
MCE_05875
Conjugative transfer protein TraD; COG3505 Type IV secretory pathway, VirD4 components.
 
   
 0.711
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 
 0.694
MCE_05885
Conjugative transfer protein TraG.
 
     0.692
MCE_05890
F pilus assembly protein TraH.
 
   
 0.666
MCE_03800
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.659
MCE_05995
Putative conjugative transfer protein TraD; COG3505 Type IV secretory pathway, VirD4 components.
 
   
 0.657
MCE_05610
Acetyltransferase GNAT family protein; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.
 
    0.641
MCE_05895
F pilus assembly protein TraF.
 
   
 0.624
Your Current Organism:
Rickettsia amblyommatis
NCBI taxonomy Id: 1105111
Other names: Candidatus Rickettsia amblyommii str. GAT-30V, R. amblyommatis str. GAT-30V, Rickettsia amblyommatis str. GAT-30V
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