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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCE_07165COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains). (822 aa)    
Predicted Functional Partners:
MCE_06015
Conjugal transfer protein TraA; COG0358 DNA primase (bacterial type).
 
 
 0.882
MCE_05865
Conjugal transfer protein TraA; COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member.
  
 
 0.857
MCE_05940
Conjugal transfer protein TraA.
  
 
 0.857
MCE_06010
Conjugal transfer protein TraA; COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member.
  
 
 0.857
MCE_03660
Hypothetical protein; COG2887 RecB family exonuclease.
 
   
 0.838
recO
DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination.
 
   
 0.712
recA
Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.704
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.670
ligA
NAD-dependent DNA ligase LigA; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
  
 
 0.668
MCE_04810
COG0350 Methylated DNA-protein cysteine methyltransferase.
     
 0.654
Your Current Organism:
Rickettsia amblyommatis
NCBI taxonomy Id: 1105111
Other names: Candidatus Rickettsia amblyommii str. GAT-30V, R. amblyommatis str. GAT-30V, Rickettsia amblyommatis str. GAT-30V
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