CG50_02880 protein (Paenirhodobacter enshiensis)

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second shell of interactors

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

CG50_02880

Flavin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (186 aa)

Predicted Functional Partners:

CG50_15020

0.592

CG50_02875

0.548

CG50_02885

0.506

CG50_06170

0.491

CG50_02870

0.416

Your Current Organism:

Paenirhodobacter enshiensis

NCBI taxonomy Id: 1105367
Other names: CCTCC AB 2011145, KCTC 15169, P. enshiensis, Paenirhodobacter enshiensis Wang et al. 2014, Rhodobacter sp. DW2-9, strain DW2-9

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Browse interactions in tabular form:

Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

11

PPI enrichment p-value:

< 1.0e-16

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
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Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016192

Vesicle-mediated transport

10 of 352

1.5

2.83

1.74e-11

GO:0006888

Endoplasmic reticulum to Golgi vesicle-mediated transport

4 of 74

1.78

1.74

0.00017

GO:0048205

COPI coating of Golgi vesicle

2 of 2

3.04

1.6

0.0013

GO:0006887

Exocytosis

3 of 38

1.94

1.45

0.0013

GO:0046907

Intracellular transport

7 of 494

1.19

1.31

2.31e-05

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005096

GTPase activator activity

7 of 122

1.8

3.21

6.20e-09

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0030126

COPI vesicle coat

2 of 9

2.39

0.81

0.0327

GO:0005794

Golgi apparatus

4 of 268

1.22

0.64

0.0327

GO:0031410

Cytoplasmic vesicle

4 of 278

1.2

0.63

0.0327

GO:0005737

Cytoplasm

10 of 4900

0.35

0.25

0.0461

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:17015

Haemolysin-III related, and ArfGAP domain superfamily

4 of 17

2.41

2.83

3.91e-06

CL:17019

ArfGAP domain superfamily

3 of 6

2.74

2.6

1.60e-05

CL:5042

COPI vesicle coat, and ADP-ribosylation factor 1-5

3 of 12

2.44

2.28

5.03e-05

CL:4742

Vesicle-mediated transport, and RAB geranylgeranylation

6 of 171

1.59

2.07

3.91e-06

CL:4747

Exocytosis, and RAB geranylgeranylation

3 of 41

1.91

1.47

0.0011

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map04144

Endocytosis

10 of 230

1.68

3.98

1.18e-14

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-6811434

COPI-dependent Golgi-to-ER retrograde traffic

4 of 65

1.83

1.69

0.00029

MAP-6807878

COPI-mediated anterograde transport

4 of 66

1.83

1.68

0.00029

MAP-8856688

Golgi-to-ER retrograde transport

4 of 80

1.74

1.63

0.00029

MAP-199977

ER to Golgi Anterograde Transport

4 of 118

1.57

1.38

0.00071

MAP-948021

Transport to the Golgi and subsequent modification

4 of 121

1.56

1.37

0.00071

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0863

Zinc-finger

7 of 466

1.22

1.41

9.42e-06

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR038508

ArfGAP domain superfamily

7 of 10

2.89

7.64

2.87e-15

IPR037278

ARFGAP/RecO-like zinc finger

7 of 10

2.89

7.64

2.87e-15

IPR001164

Arf GTPase activating protein

7 of 10

2.89

7.64

2.87e-15

IPR005225

Small GTP-binding protein domain

3 of 76

1.64

0.72

0.0364

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00105

Putative GTP-ase activating proteins for the small GTPase, ARF

7 of 10

2.89

8.12

3.13e-16

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node1	node2	node1 annotation	node2 annotation	score
CG50_02870	CG50_02875	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Flavin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.569
CG50_02870	CG50_02880	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Flavin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.416
CG50_02875	CG50_02870	Flavin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.569
CG50_02875	CG50_02880	Flavin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Flavin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.548
CG50_02875	CG50_06170	Flavin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.491
CG50_02875	CG50_15020	Flavin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dihydropyrimidine dehydrogenase; NADH-dependent; catalyzes the conversion of pyrimidines to 5,6-dihydro compounds in pyrimidine degradation; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.592
CG50_02880	CG50_02870	Flavin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.416
CG50_02880	CG50_02875	Flavin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Flavin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.548
CG50_02880	CG50_02885	Flavin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Alpha-amylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.506
CG50_02880	CG50_06170	Flavin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.491
CG50_02880	CG50_15020	Flavin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dihydropyrimidine dehydrogenase; NADH-dependent; catalyzes the conversion of pyrimidines to 5,6-dihydro compounds in pyrimidine degradation; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.592
CG50_02885	CG50_02880	Alpha-amylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Flavin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.506
CG50_02885	CG50_06170	Alpha-amylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.402
CG50_06170	CG50_02875	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Flavin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.491
CG50_06170	CG50_02880	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Flavin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.491
CG50_06170	CG50_02885	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Alpha-amylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.402
CG50_15020	CG50_02875	Dihydropyrimidine dehydrogenase; NADH-dependent; catalyzes the conversion of pyrimidines to 5,6-dihydro compounds in pyrimidine degradation; Derived by automated computational analysis using gene prediction method: Protein Homology.	Flavin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.592
CG50_15020	CG50_02880	Dihydropyrimidine dehydrogenase; NADH-dependent; catalyzes the conversion of pyrimidines to 5,6-dihydro compounds in pyrimidine degradation; Derived by automated computational analysis using gene prediction method: Protein Homology.	Flavin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.592