STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
pxr2Aristolochene synthase prx2; Aristolochene synthase; part of the gene cluster that mediates the biosynthesis of PR-toxin, a bicyclic sesquiterpene belonging to the eremophilane class and acting as a mycotoxin. The first step of the pathway is catalyzed by the aristolochene synthase which performs the cyclization of trans,trans- farnesyl diphosphate (FPP) to the bicyclic sesquiterpene aristolochene. Following the formation of aristolochene, the non- oxygenated aristolochene is converted to the trioxygenated intermediate eremofortin B. This conversion appears to involve three enzymes, a [...] (342 aa)    
Predicted Functional Partners:
Pc21g13930
Pc21g13930 protein.
  
 0.946
Pc21g15240
Pc21g15240 protein; Belongs to the FPP/GGPP synthase family.
    
 0.879
Pc16g00980
Pc16g00980 protein.
  
 
 0.870
Pc22g05810
Pc22g05810 protein.
  
 
 0.870
Pc13g07290
Pc13g07290 protein.
     
 0.847
Pc20g07830
Pc20g07830 protein; Belongs to the FPP/GGPP synthase family.
     
 0.845
Pc22g12410
Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.
   
 0.831
Pc13g12220
Pc13g12220 protein; Belongs to the FPP/GGPP synthase family.
     
  0.800
Pc20g01860
Pc20g01860 protein; Belongs to the FPP/GGPP synthase family.
     
  0.800
Pc22g18320
Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family.
  
 0.640
Your Current Organism:
Penicillium rubens
NCBI taxonomy Id: 500485
Other names: P. rubens Wisconsin 54-1255, Penicillium rubens Wisconsin 54-1255
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.