node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PIIN_00875 | PIIN_01546 | G4T6U8 | G4T8S7 | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | 0.965 |
PIIN_00875 | PIIN_01957 | G4T6U8 | G4T9T6 | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Related to LPD1-dihydrolipoamide dehydrogenase. | 0.994 |
PIIN_00875 | PIIN_03937 | G4T6U8 | G4TFB9 | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Probable methylcrotonoyl-CoA carboxylase biotin carboxylase chain. | 0.907 |
PIIN_00875 | PIIN_04011 | G4T6U8 | G4TFG8 | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.831 |
PIIN_00875 | PIIN_04897 | G4T6U8 | G4TI19 | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Probable branched-chain alpha-keto acid dehydrogenase e1-beta subunit. | 0.699 |
PIIN_00875 | PIIN_05877 | G4T6U8 | G4TKU9 | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Probable oxoglutarate dehydrogenase. | 0.819 |
PIIN_00875 | PIIN_07275 | G4T6U8 | G4TPS7 | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Probable KGD1-alpha-ketoglutarate dehydrogenase. | 0.906 |
PIIN_00875 | PIIN_08194 | G4T6U8 | G4TSE8 | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | 0.999 |
PIIN_00875 | PIIN_08681 | G4T6U8 | G4TTS8 | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Probable isovaleryl-CoA dehydrogenase. | 0.568 |
PIIN_00875 | PIIN_08818 | G4T6U8 | G4TU56 | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Dihydrolipoyl dehydrogenase. | 0.995 |
PIIN_01546 | PIIN_00875 | G4T8S7 | G4T6U8 | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.965 |
PIIN_01546 | PIIN_01957 | G4T8S7 | G4T9T6 | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | Related to LPD1-dihydrolipoamide dehydrogenase. | 0.975 |
PIIN_01546 | PIIN_03937 | G4T8S7 | G4TFB9 | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | Probable methylcrotonoyl-CoA carboxylase biotin carboxylase chain. | 0.929 |
PIIN_01546 | PIIN_04011 | G4T8S7 | G4TFG8 | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.930 |
PIIN_01546 | PIIN_04897 | G4T8S7 | G4TI19 | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | Probable branched-chain alpha-keto acid dehydrogenase e1-beta subunit. | 0.994 |
PIIN_01546 | PIIN_05877 | G4T8S7 | G4TKU9 | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | Probable oxoglutarate dehydrogenase. | 0.956 |
PIIN_01546 | PIIN_07275 | G4T8S7 | G4TPS7 | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | Probable KGD1-alpha-ketoglutarate dehydrogenase. | 0.959 |
PIIN_01546 | PIIN_08194 | G4T8S7 | G4TSE8 | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | 0.993 |
PIIN_01546 | PIIN_08681 | G4T8S7 | G4TTS8 | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | Probable isovaleryl-CoA dehydrogenase. | 0.929 |
PIIN_01546 | PIIN_08818 | G4T8S7 | G4TU56 | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | Dihydrolipoyl dehydrogenase. | 0.984 |