STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PIIN_01679Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (370 aa)    
Predicted Functional Partners:
PIIN_08322
Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.
   
 0.991
PIIN_00521
BPL/LPL catalytic domain-containing protein.
 
 
 0.939
PIIN_00248
U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
  
 
 0.932
PIIN_03006
Probable ribosomal protein L13a; Belongs to the universal ribosomal protein uL13 family.
      0.816
PIIN_06993
Probable NIT2-nitrilase.
  
 
 0.668
PIIN_03316
Related to NFU-1 protein (Iron homeostasis).
  
 
 0.633
PIIN_06235
Probable isopentenyl-diphosphate delta-isomerase.
 
    0.628
PIIN_08638
Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
 
      0.613
PIIN_03597
Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family.
     
 0.612
PIIN_04157
Probable nitrilase (NIT3).
  
 
 0.608
Your Current Organism:
Serendipita indica
NCBI taxonomy Id: 1109443
Other names: Piriformospora indica DSM 11827, S. indica DSM 11827, Serendipita indica DSM 11827
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